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Dobutaminum [Inn-Latin]: Full Drug Profile

Medically reviewed by Min Clinic Staff | Updated: January 2026

Dobutaminum [Inn-Latin] - General Information

A beta-2 agonist catecholamine that has cardiac stimulant action without evoking vasoconstriction or tachycardia. It is proposed as a cardiotonic after myocardial infarction or open heart surgery. [PubChem]

 

Pharmacology of Dobutaminum [Inn-Latin]

Dobutaminum [Inn-Latin] is a direct-acting inotropic agent whose primary activity results from stimulation of the beta-adrenoceptors of the heart while producing comparatively mild chronotropic, hypertensive, arrhythmogenic, and vasodilative effects. Dobutaminum [Inn-Latin] acts primarily on beta-1 adrenergic receptors, with little effect on beta-2 or alpha receptors. It does not cause the release of endogenous norepinephrine, as does dopamine. Dobutaminum [Inn-Latin] is indicated when parenteral therapy is necessary for inotropic support in the short-term treatment of patients with cardiac decompensation due to depressed contractility resulting either from organic heart disease or from cardiac surgical procedures.

 

Dobutaminum [Inn-Latin] for patients

 

Dobutaminum [Inn-Latin] Interactions

Animal studies indicate that dobutamine may be ineffective if the patient has recently received a b-blocking drug. In such a case, the peripheral vascular resistance may increase.

Preliminary studies indicate that the concomitant use of dobutamine and nitroprusside results in a higher cardiac output and, usually, a lower pulmonary wedge pressure than when either drug is used alone.

There was no evidence of drug interactions in clinical studies in which dobutamine was administered concurrently with other drugs, including digitalis preparations, furosemide, spironolactone, lidocaine, glyceryl trinitrate, isosorbide dinitrate, morphine, atropine, heparin, protamine, potassium chloride, folic acid, and acetaminophen.

 

Dobutaminum [Inn-Latin] Contraindications

Dobutamine is contraindicated in patients with idiopathic hypertrophic subaortic stenosis and in patients who have shown previous manifestations of hypersensitivity to dobutamine.

 

Additional information about Dobutaminum [Inn-Latin]

Dobutaminum [Inn-Latin] Indication: For inotropic support in the short- term treatment of patients with cardiac decompensation due to depressed contractility resulting either from organic heart disease or from cardiac surgical procedures Mechanism Of Action: Dobutaminum [Inn-Latin] directly stimulates beta-1 receptors of the heart to increase myocardial contractility and stroke volume, resulting in increased cardiac output. Drug Interactions: Not Available Food Interactions: Not Available Generic Name: Dobutamine Synonyms: Not Available Drug Category: Cardiotonic Agents; Sympathomimetic Drug Type: Small Molecule; Approved Other Brand Names containing Dobutamine: Dobutamina [Inn-Spanish]; Dobutamine Hcl; Dobutamine Hcl in Dextrose 5%; Dobutamine Hydrochloride; Dobutamine [Usan-Ban-Inn]; Dobutamine [Usan]; Dobutaminum [Inn-Latin]; Dobutrex; Inotrex; Racemic-Dobutamine; Absorption: Not Available Toxicity (Overdose): Not Available Protein Binding: Not Available Biotransformation: Not Available Half Life: 2 minutes Dosage Forms of Dobutaminum [Inn-Latin]: Solution IntravenousLiquid Intravenous Chemical IUPAC Name: 4-[2-[4-(4-hydroxyphenyl)butan-2-ylamino]ethyl]benzene-1,2-diol Chemical Formula: C18H23NO3 Dobutamine on Wikipedia: https://en.wikipedia.org/wiki/Dobutamine Organisms Affected: Humans and other mammals